Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Odontogenesis: Cell–Cell Interactions in vitro

Nature volume 217, pages 269–270 (1968)Cite this article

Abstract

EMBRYONIC interactions of epithelial and mesenchymal tissue before organogenesis have been observed in several organ systems1–4. These phenomena have been tested by isolating embryonic tissues from their in vivo environment and transplanting them in an artificial environment from which no morphogenetic signals can be received. The chorio-allantoic membrane (CAM) of chick provides a versatile site for the maintenance and further differentiation of embryonic organs5,6. One such organ, the tooth primordium, arises as a result of interactions between epithelial and mesenchymal tissues and offers a model system for developmental studies.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Saunders, J. W., Cairns, J. M., and Gasseling, M. T., J. Morphol., 101, 57 (1957).

    Article  Google Scholar 

  2. Rawles, M. E., J. Embryol. Exp. Morphol, 11, 765 (1963).

    CAS  PubMed  Google Scholar 

  3. Auerbach, R., Develop. Biol., 2, 271 (1960).

    Article  CAS  PubMed  Google Scholar 

  4. Grobstein, C., J. Exp. Zool., 124, 383 (1953).

    Article  Google Scholar 

  5. Glasstone, S., J. Anat., 88, 392 (1954).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Slavkin, H. C., and Bavetta, L. A., Experientia (in the press).

  7. Koch, W., J. Exp. Zool., 165, 155 (1967).

    Article  CAS  PubMed  Google Scholar 

  8. Hay, M. F., Arch. Oral Biol., 3, 86 (1961).

    Article  CAS  PubMed  Google Scholar 

  9. Lefkowitz, W., Bodecker, C. F., and Mardfin, D. F., J. Dent. Rest., 32, 749 (1953).

    Article  CAS  Google Scholar 

  10. Paynter, K. L., and Hunt, A. M., Arch. Oral Biol., 9, 611 (1964).

    Article  CAS  PubMed  Google Scholar 

  11. Pourtois, M., J. Embryol. Exp. Morphol., 12, 391 (1964).

    CAS  PubMed  Google Scholar 

  12. Slavkin, H. C., and Bavetta, L. A., Arch. Oral Biol. (in the press).

  13. Moscona, A. A., Exp. Cell Res., 22, 455 (1961).

    Article  CAS  PubMed  Google Scholar 

  14. Hunt, A. M., and Paynter, K. J., Arch. Oral Biol., 8, 65 (1963).

    Article  CAS  PubMed  Google Scholar 

  15. Zussman, W. V., Oral Surg., Oral Med. and Oral Path., 21, 217 (1966).

    Article  CAS  Google Scholar 

  16. Glasstone, S., Proc. Roy. Soc., B, 126, 315 (1938).

    ADS  Google Scholar 

  17. Huggins, C. B., McCarroll, H. R., and Dahlberg, A. A., J. Exp. Med., 60, 199 (1934).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Fleming, H. S., J. Dent. Res., 31, 166 (1952).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, School of Dentistry, University of Southern California, Los Angeles, California

    H. C. SLAVKIN, J. BEIERLE & L. A. BAVETTA

Authors
  1. H. C. SLAVKIN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. BEIERLE
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. A. BAVETTA
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SLAVKIN, H., BEIERLE, J. & BAVETTA, L. Odontogenesis: Cell–Cell Interactions in vitro. Nature 217, 269–270 (1968). https://doi.org/10.1038/217269a0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/217269a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing