Abstract
WE have found that the polysaccharide preparation, termed hemicellulose B, isolated from wheat straw is highly active in inhibiting the growth and inducing regression of sarcoma 180 subcutaneously implanted in mice. The polysaccharide preparation has, however, only a slight effect on subcutaneous grafts of Ehrlich carcinoma and no recognizable effect on the growth of autologous grafts of spontaneous mammary adenocarcinomas. Certain polysaccharides from higher plants have been shown to inhibit growth of transplanted tumours, but the polymers also appeared toxic and none were well characterized1–13. Statolon from P. stoloniferium induces the production of interferon in animal cells14.
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NAKAHARA, W., TOKUZEN, R., FUKUOKA, F. et al. Inhibition of Mouse Sarcoma 180 by a Wheat Hemicellulose B Preparation. Nature 216, 374–375 (1967). https://doi.org/10.1038/216374a0
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DOI: https://doi.org/10.1038/216374a0
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