Abstract
IN suitable conditions, anti-γ-globulin inhibits lysis of sensitized red cells1. Rheumatoid factor is apparently an antibody against γ-globulin, and so it might be expected to do the same. This report describes the results of “inhibition of lysis” titrations on sera from normal subjects and patients with rheumatoid arthritis, and shows that the correlation with sensitized sheep cell agglutination tests and latex fixation tests is high.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Romeyn, J. A., and Onysko, E., Immunology, 7, 217 (1964).
Heimer, R., Levin, F. M., and Kahn, M. F., J. Immunol., 91, 866 (1963).
Heimer, R., and Levin, F., Ann. NY Acad. Sci., 124, 789 (1965).
Williams, R. C., and Kunkel, H. G., Arthr. and Rheum., 6, 665 (1963).
Heimer, R., Levin, F. M., Primack, A., Corcos, J. M., and Nosenzo, C., J. Immunol., 89, 382 (1962).
Schmid, F. R., and Roitt, I. M., J. Lab. Clin. Med., 66, 1019 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROMEYN, J., BOWMAN, D. Inhibition of Complementary Lysis by Rheumatoid Sera. Nature 216, 180–181 (1967). https://doi.org/10.1038/216180a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/216180a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.