Abstract
CAPTAN (N-trichloromethylthio-4-cyclohexene-1,2-dicarboxyimide) is an agricultural fungicide of low mammalian toxicity, and its residues*; in agricultural products are considered to offer less risk than most pesticides. A recent report1 draws attention to the mutagenic and teratogenic properties of captan, which has been observed to increase the mutation rate in bacteria (Escherichia coli), to inhibit mitotic division in the cell cultures and to induce physical abnormalities in chicks treated in the embryonic stage.
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References
Legator, M., and Verrett, J., New York Academy of Sciences, Conference on Biological Effects of Pesticides in Mammalian Systems”, abstract of paper 6, 17 (1967).
Richmond, D. V., and Somers, E., Ann. Appl. Biol., 50, 33 (1962).
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ABEDI, Z., MCKINLEY, W. Bioassay of Captan by Zebrafish Larvae. Nature 216, 1321–1322 (1967). https://doi.org/10.1038/2161321a0
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DOI: https://doi.org/10.1038/2161321a0
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