Abstract
IT has been known, for many years that, following a large haemorrhage, dog plasma develops the ability to stimulate smooth muscle in vitro1,2 and to increase the blood pressure when injected into anephric dogs3–6. These experiments suggested that the concentration of renin and angiotensin in the blood might be increased in such circumstances, and this has been confirmed in more recent studies, which have shown, that both the concentration of angiotensin in. the blood7–9 and the concentration of plasma renin10 are increased after heavy bleeding in the dog.
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BROWN, J., LEVER, A., ROBERTSON, J. et al. Concurrent Measurement of Renin and Angiotensin in the Circulation of the Dog. Nature 215, 853–855 (1967). https://doi.org/10.1038/215853a0
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DOI: https://doi.org/10.1038/215853a0
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