Abstract
TISSUE culture lines of human tumours can be transplanted into animal hosts conditioned with immunological depressants such as cortisone or irradiation1. Several reports2,3 describe the immunosuppressive action of antilymphocyte serum; mice treated with antilymphocyte serum have a reduced capacity to reject skin homografts. Antilymphocyte serum seems to be the most effective immunosuppressant yet discovered, and because of its specificity and low toxicity it may provide an improved alternative to methods of host conditioning at present used in tumour transplantation. We have been able to grow two human tumour cell lines in mice treated with antilymphocyte serum.
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References
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PHILLIPS, B., GAZET, JC. Growth of Two Human Tumour Cell Lines in Mice treated with Antilymphocyte Serum. Nature 215, 548–549 (1967). https://doi.org/10.1038/215548a0
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DOI: https://doi.org/10.1038/215548a0
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