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A 3-Amino-3.6-dideoxyhexose from the Lipopolysaccharide of Escherichia coli 071

Abstract

FOR a long time fungi were the only known source of naturally occurring 3-amino-3.6-dideoxyhexoses1. It was only in 1965 that a representative of this group of amino sugars was reported to be present also in bacteria by Ashwell et al.2, who isolated 3-amino-3.6-dideoxy-D-galactose from a phenol soluble lipopolysaccharide of Xanthomonas campestris. Later 3-amino-3.6-dideoxy-D-galactose was also isolated from the lipopolysaccharides of several Escherichia coli strains (unpublished work of Jann, Jann and Müller-Seitz). Recently, a 3-amino-3.6-dideoxyhexose was found in a glycoprotein complex of Citrobacter freundii3. In the lipopolysaccharides of Salmonella group M a 3-amino-3.6-dideoxyhexose was detected (Lüderitz, O., private communication). This communication concerns the isolation of a 3-amino-3.6-dideoxyhexose from the lipopolysaccharide of E. coli 071 and its tentative identification as 3-amino-3.6-dideoxyglucose.

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JANN, B., JANN, K. & MÜLLER-SEITZ, E. A 3-Amino-3.6-dideoxyhexose from the Lipopolysaccharide of Escherichia coli 071. Nature 215, 170–171 (1967). https://doi.org/10.1038/215170a0

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