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Structure of N-terminal Fragments of Fibrinogen and Specificity of Thrombin

Nature volume 215, pages 1445–1448 (1967)Cite this article

Abstract

Determination of the amino-acid sequences of N-terminal fragments from human fibrinogen A and B chains shows that this region of the molecule is highly cross-linked with disulphide bridges and suggests why the proteolytic action of thrombin is so highly specific.

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Authors and Affiliations

  1. Department of Blood Coagulation Research, Karolinska Institutet, Stockholm

    B. BLOMBÄCK, M. BLOMBÄCK, B. HESSEL & S. IWANAGA

Authors
  1. B. BLOMBÄCK
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  2. M. BLOMBÄCK
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  3. B. HESSEL
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  4. S. IWANAGA
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BLOMBÄCK, B., BLOMBÄCK, M., HESSEL, B. et al. Structure of N-terminal Fragments of Fibrinogen and Specificity of Thrombin. Nature 215, 1445–1448 (1967). https://doi.org/10.1038/2151445a0

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