Abstract
MEASUREMENT of the adhesiveness of platelets in vitro has yielded variable results in von Willebrand's disease1–6. Hopes of increasing the discrimination between von Willebrand's disease and normal subjects using adenosine diphosphate (ADP) in an in vitro system have not been fulfilled2,3,6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hellem, A. J., Scand. J. Clin. Lab. Invest., suppl. 51 (1960).
Salzman, E. W., J. Lab. Clin. Med., 62, 724 (1963).
O'Brien, J. R., J. Clin. Path., 14, 140 (1961).
Cronberg, S., Nilsson, I. M., and Silwer, J., Acta Med. Scand., 180, 43 (1966).
Zucker, M. B., Nature, 197, 601 (1963).
Ödegaard, A. E., Skålhegg, B. A., and Hellem, A. J., Thromb. Diath. Haemorrh., 11, 23 (1964).
Borchgrevink, C. F., Acta Med. Scand., 170, 231 (1961).
Blair, E. L., Wakefield, M., Ingram, G. I. C., and Armitage, P., Nature, 176 563 (1955).
McClure, P. D., Ingram, G. I. C., Stacey, R. S., Glass, U. H., and Matchett, M. O., Brit. J. Haem., 12, 478 (1966).
Brecher, G., and Cronkite, E. P., J. App. Physiol., 3, 365 (1950).
Ingram, G. I. C., J. Physiol., 156, 217 (1961).
Hardisty, R. M., and MacPherson, J. C., Thromb. Diath. Haemorrh., 7, 215 (1962).
Marr, J., Barboriak, J. J., and Johnson, S. A., Nature, 205, 259 (1965).
Ireland, D. M., and Mills, D. C. B., Biochem. J., 92, 30 (1964).
Constantine, J. W., Amer. J. Physiol., 209, 409 (1965).
Born, G. V. R., Nature, 194, 927 (1962).
Born, G. V. R., and Cross, M. J., J. Physiol., 168, 178 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LESLIE, J. Bleeding Time and in vivo Platelet Adhesiveness in von Willebrand's Disease: Effect of Iontophoresis of Adenosine Diphosphate. Nature 215, 1302–1303 (1967). https://doi.org/10.1038/2151302a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2151302a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
