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Choline and Phospholipid-choline in a Sympathetic Ganglion and their Relationship to Acetylcholine Synthesis

Abstract

INDIRECT evidence suggests that the preganglionic nerve terminals of the superior cervical ganglion of the cat can store appreciable quantities of choline for the synthesis of acetylcholine. Choline could be stored either as choline and/or as choline esterified to phospholipids (PL-choline).

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References

  1. Birks, R., and MacIntosh, F. C., Canad. J. Biochem. Physiol., 39, 787 (1961).

    Article  CAS  Google Scholar 

  2. Perry, W. L. M., J. Physiol., 119, 439 (1953).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Crossland, J., Methods Med. Res., 9, 125 (1961).

    CAS  PubMed  Google Scholar 

  4. MacIntosh, F. C., and Perry, W. L. M., Methods Med. Res., 3, 78 (1950).

    Google Scholar 

  5. Emmelin, N., and MacIntosh, F. C., J. Physiol., 131, 477 (1956).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Hanahan, D. J., Lipids Chemistry, 88 (John Wiley and Sons Inc., New York, 1960).

    Google Scholar 

  7. Matthews, E. K., Brit. J. Pharmacol., 26, 552 (1966).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Brown, G. L., and Feldberg, W., J. Physiol., 88, 265 (1936).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Folch, J., Lees, M., and Stanley, G. H. S., J. Biol. Chem., 226, 497 (1957).

    CAS  PubMed  Google Scholar 

  10. Brown, G. L., and Feldberg, W., J. Physiol., 86, 290 (1936).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Feldberg, W., J. Physiol., 101, 432 (1943).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Friesen, A. J. D., Kemp, J. W., and Woodbury, D. M., J. Pharmacol. Exp. Therap., 148, 312 (1965).

    CAS  Google Scholar 

  13. Larrabee, M. G., and Leicht, W. S., J. Neurochem., 12, 1 (1965).

    Article  CAS  PubMed  Google Scholar 

Download references

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FRIESEN, A., LING, G. & NAGAI, M. Choline and Phospholipid-choline in a Sympathetic Ganglion and their Relationship to Acetylcholine Synthesis. Nature 214, 722–724 (1967). https://doi.org/10.1038/214722a0

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