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New Peripheral Antagonists of 5-Hydroxytryptamine

Nature volume 214, pages 200–201 (1967)Cite this article

Abstract

PHARMACOLOGICAL screening of a series of guanidines1, formally related to the quaternary ammonium anthelmintic compound bephenium and its congeners2, revealed that B.W. 712C60 [(I), R1 = R2 = phenyl; A = (CH2)2] although devoid of such anthelmintic activity antagonized 5-hydroxytryptamine (5HT).

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References

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Authors and Affiliations

  1. The Wellcome Research Laboratories, Beckenham, Kent

    F. C. COPP, A. F. GREEN, H. F. HODSON, A. W. RANDALL & M. F. SIM

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  1. F. C. COPP
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  2. A. F. GREEN
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  3. H. F. HODSON
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  4. A. W. RANDALL
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  5. M. F. SIM
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COPP, F., GREEN, A., HODSON, H. et al. New Peripheral Antagonists of 5-Hydroxytryptamine. Nature 214, 200–201 (1967). https://doi.org/10.1038/214200a0

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