Abstract
PREVIOUS investigations from this laboratory have demonstrated the production of protoplasts* in kidneys of rats by treatment of acute enterococcal pyelonephritis with penicillin1. Furthermore, reports of isolation of these forms from patients have appeared in the literature. Although these observations do not satisfy Koch's postulates2 for proof of pathogenicity, the possibility exists that these forms could play a part in the pathogenesis of disease by a variety of mechanisms. Investigation of host–parasite interaction has been made and the present report describes the killing of microbial protoplasts by serum.
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GUZE, L., HUBERT, E., MONTGOMERIE, J. et al. Observations on the Killing of Microbial Protoplasts by Serum. Nature 214, 1343–1344 (1967). https://doi.org/10.1038/2141343a0
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DOI: https://doi.org/10.1038/2141343a0
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