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Catabolism of Tryptophan by the Isolated, Perfused Liver and Intestine

Abstract

THE metabolism of tryptophan has received considerable attention from biochemists1,2 and has been of particular interest because a number of physiologically active agents, such as serotonin, are among the many metabolites of tryptophan. Information about tryptophan metabolites is extensive in a qualitative sense, but quantitative data on tryptophan catabolism in various organs are scarce. The present communication deals with certain quantitative aspects of tryptophan metabolism in the perfused liver and intestine of the rat.

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ALTMAN, K., GERBER, G. Catabolism of Tryptophan by the Isolated, Perfused Liver and Intestine. Nature 213, 911–913 (1967). https://doi.org/10.1038/213911a0

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