Abstract
THE metabolism of tryptophan has received considerable attention from biochemists1,2 and has been of particular interest because a number of physiologically active agents, such as serotonin, are among the many metabolites of tryptophan. Information about tryptophan metabolites is extensive in a qualitative sense, but quantitative data on tryptophan catabolism in various organs are scarce. The present communication deals with certain quantitative aspects of tryptophan metabolism in the perfused liver and intestine of the rat.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dalgliesh, C. F., Adv. Protein Chem., 10, 103 (1955).
Meister, A., Biochemistry of Amino-Acids, second ed. (Academic Press, New York, 1965).
Green, M., and Miller, L. L., J. Biol. Chem., 235, 3202 (1960).
Gerber, G. B., and Remy-Defraigne, J., Arch. Internat. Physiol. Biochim., 74, 785 (1966).
Duggan, D. E., and Udenfriend, S., J. Biol. Chem., 223, 313 (1956).
Knox, W. E., Brit. J. Exp. Pathol., 32, 462 (1951).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ALTMAN, K., GERBER, G. Catabolism of Tryptophan by the Isolated, Perfused Liver and Intestine. Nature 213, 911–913 (1967). https://doi.org/10.1038/213911a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/213911a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.