Abstract
THE lens of the eye is an ideal system for the examination of cell differentiation because of its isolation from the blood stream, lack of connective tissue and because it includes only cells derived from ectoderm. Furthermore, with the epithelial cell, the annular pad cell and the cortical and nuclear fibre cell, the lens cell shows a sequence of progressive differentiation. The lens lacks a mechanism for discarding cells, and so has within its structure a complete record of its embryonic and adult differentiation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Maisel, H., Kerrigan, M., and Syner, F., Invest. Ophthal., 4, 362 (1965).
Smithies, T. O., Biochem. J., 71, 585 (1959).
Maisel, H., and Goodman, M., Invest. Ophthal., 4, 129 (1965).
Kornberg, A., in Methods of Enzymology (edit. by Colowick, A. P., and Kaplan, N. O.), 6 (Academic Press, Inc., New York, 1963).
Cahn, R. D., Kaplan, N. O., Levine, L., and Zwilling, E., Science, 136, 962 (1962).
Vesell, E. S., Science, 150, 1735 (1965).
Stewart, J. A., and Papaconstantinou, J., Fed. Proc., 24, 667 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GENIS-GALVEZ, J., MAISEL, H. Lactic Dehydrogenase Isozymes: Changes during Lens Differentiation in the Chick. Nature 213, 283–285 (1967). https://doi.org/10.1038/213283a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/213283a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
