Abstract
Some mice of the AKR strain reared under germfree conditions become thin and “hunched up”, with rough wet fur, depilation around the anus, shrunken thymus and enlarged lymph nodes. The histological appearance of the thymus and lymphoid tissue is similar to that in the early stages of mouse leukaemia
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References
Glimstedt, G., Nord. Med. Tidskr., 14, 1269 (1937).
Gordon, H. A., Ann. N.Y. Acad. Sci., 78, 208 (1959).
Thorbecke, G. J., Ann. N.Y. Acad. Sci., 78, 237 (1959).
Bauer, H., Horowitz, R. E., Levenson, S. M., and Popper, H., Amer. J. Pathol., 42, 471 (1963).
Dunn, T. B., J. Nat. Cancer Inst., 14, 1281 (1954).
Grabar, P., Courcon, J., and Wostmann, B. S., J. Immunology, 88, 679 (1962).
Wostmann, B. S., Ann. N.Y. Acad. Sci., 78, 254 (1959).
Bealmear, M., and Wilson, R., Anat. Rec., 154, 261 (1966).
de Harven, E., J. Exp. Med., 120, 857 (1964).
Pollard, M., and Matsuzawa, T., Proc. Soc. Exp. Biol. and Med., 16, 967 (1964).
Kajima, M., and Pollard, M., J. Bact., 90, 1448 (1965).
Wagner, M., Ann. N.Y. Acad. Sci., 78, 89 (1959).
Gilbey, J. G., and Pollard, M., J. Nat. Cancer Inst. (in the press).
Pollard, M., Teah, B. A., and Matsuzawa, T., Proc. Soc. Exp. Biol. and Med., 120, 72 (1965).
Krum bhaar, E. B., Blood, 3, 953 (1948).
Simonsen, M., Engelbreth-Holm, J., Jensen, E., and Poulsen, H., Ann. N.Y. Acad. Sci., 73, 834 (1958).
Siskind, G. W., and Thomas, L., J. Exp. Med., 110, 511 (1959).
Simonsen, M., Acta Pathol. and Microbiol. Scand., 40, 480 (1957).
Billingham, R. E., Ann. N.Y. Acad. Sci., 73, 782 (1958).
Siegler, R., and Rich, M. A., Cancer Res., 23, 1669 (1963).
Pollard, M., Bact. Proc., 134 (1964).
Dameshek, W., Israel J. Med. Sci., 1, 1304 (1965).
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POLLARD, M. Preleukaemic Syndrome in Germfree AKR Mice. Nature 213, 142–144 (1967). https://doi.org/10.1038/213142a0
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DOI: https://doi.org/10.1038/213142a0
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