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Induction of Tumours in Denervated Skin

Abstract

IT has been shown that the number of fine axons in close relationship with the epidermis of human skin increases pari passu with a rise in the mitotic index in the germinal layer1,2. These observations prompted us to compare the rate of tumour induction by chemical carcinogenic agents in comparable zones of healthy as well as denervated skin in the same animal, because it has been shown that in completely denervated skin the mitotic index falls3.

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References

  1. Weddell, G., Cowan, M. A., Palmer, E., and Ramaswamy, S., Arch. Derm., 91, 252 (1965).

    Article  CAS  Google Scholar 

  2. Allenby, C. F., Palmer, E., and Weddell, G., Zeit.für Zellf., 69, 566 (1966).

    Article  CAS  Google Scholar 

  3. Kulagin, A. N., Bull. Exp. Biol. Med., 49, 525 (1960).

    Article  Google Scholar 

  4. Feldberg, W., J. Physiol., 61, 518 (1926).

    Article  CAS  Google Scholar 

  5. Grant, R. T., and Thompson, R. H. S., J. Anat., 97, 7 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Weddell, G., Pallie, W., and Palmer, E., J. Anat., 89, 162 (1955).

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Grant, R. T., Bland, E. F., and Camp, P. D., Heart, 16, 69 (1932).

    Google Scholar 

  8. Richardson, K. C., J. Anat., 94, 457 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

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PAWLOWSKI, A., WEDDELL, G. Induction of Tumours in Denervated Skin. Nature 213, 1234–1236 (1967). https://doi.org/10.1038/2131234a0

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