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Effect of Anti-rat Lymphocyte Antibody on Humoral Antibody Formation

Nature volume 213, pages 1195–1197 (1967)Cite this article

Abstract

Injections of rabbit and horse anti-lymphocytic sera into hooded rats inhibited the primary humoral antibody response to sheep erythrocytes, but did not have a marked effect on the secondary response. The major part of the immunosuppressive activity was associated with the IgG fraction. Antibody fragments were not effective in suppressing the immune reaction.

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Authors and Affiliations

  1. Department of Surgical Science and Medical Research Council Research Group on Clinical and Experimental Problems of Transplantation, The Medical School, Edinburgh, Scotland

    K. JAMES & N. F. ANDERSON

Authors
  1. K. JAMES
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  2. N. F. ANDERSON
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JAMES, K., ANDERSON, N. Effect of Anti-rat Lymphocyte Antibody on Humoral Antibody Formation. Nature 213, 1195–1197 (1967). https://doi.org/10.1038/2131195a0

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