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Biochemical and Histochemical Observations on Aminopeptidase Activity in Early Wound Healing

Nature volume 213, pages 1037–1038 (1967)Cite this article

Abstract

LACK of investigations into the earliest phase of healing has supported the prevalent view that an inert lag period occurs up to the third or fifth day after wounding. Histochemically, however, the activity of several hydrolytic, transferring and oxidative enzymes has been demonstrated to increase during the very first post-operative hours1–3. An increase in aminopeptidase activity is histochemically demonstrable 2 h after the injury1. We have also investigated this enzyme biochemically during the earliest phase of wound healing.

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References

  1. Raekallio, J., Nature, 188, 234 (1960).

    Article  ADS  CAS  Google Scholar 

  2. Raekallio, J., Ann. Med. Exp. Fenn., 39, Suppl. 6 (1961).

  3. Raekallio, J., Exp. Mol. Path., 4, 303 (1965).

    Article  CAS  Google Scholar 

  4. Goldbarg, J. A., and Rutenberg, A. M., Cancer, 11, 283 (1958).

    Article  CAS  Google Scholar 

  5. Nachlas, M. M., Crawford, D. T., and Seligman, A. M., J. Histochem-Cytochem., 5, 264 (1957).

    Article  CAS  Google Scholar 

  6. Raekallio, J., Die Altersbestimmung mechanisch bedingter Hautwunden mit enzymhistochemischen Methoden, 76 (Verlag Max Schmidt-Römhild, Lübeck, 1965).

    Google Scholar 

  7. Menkin, V., Ann. N.Y. Acad. Sci., 59, 956 (1955).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Forensic Medicine, University of Turku, Turku, 3, Finland

    J. RAEKALLIO & P.-L. MÄKINEN

Authors
  1. J. RAEKALLIO
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  2. P.-L. MÄKINEN
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RAEKALLIO, J., MÄKINEN, PL. Biochemical and Histochemical Observations on Aminopeptidase Activity in Early Wound Healing. Nature 213, 1037–1038 (1967). https://doi.org/10.1038/2131037a0

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