Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Excess α Chain Synthesis Relative to β Chain Synthesis in Thalassaemia Major and Minor

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Weatherall, D. J., The Thalassemia Syndromes (Blackwell Scientific Publications, Oxford, 1965).

    Google Scholar 

  2. Pauling, L., The Harvey Lectures, Series 49, 216 (1954).

  3. Itano, H., Adv. Protein Chem., 12, 216 (1957).

    Google Scholar 

  4. Ingram, V. M., and Stretton, A. O. W., Nature, 184, 1903 (1959).

    Article  ADS  CAS  Google Scholar 

  5. Guidotti, G., referred to by Ingram, V. M., The Haemoglobins in Genetics and Evolution, 116 (Columbia University Press, New York, 1963).

    Google Scholar 

  6. Burka, E. R., and Marks, P. A., Nature, 199, 706 (1963).

    Article  ADS  CAS  Google Scholar 

  7. Bank, A., and Marks, P. A., J. Clin. Invest., 45, 330 (1966).

    Article  CAS  Google Scholar 

  8. Weatherall, D. J., Clegg, J. B., and Naughton, M. A., Nature, 208, 1061 (1965).

    Article  ADS  CAS  Google Scholar 

  9. Heywood, D., Karon, M., and Weissman, S., J. Lab. and Clin. Med., 66, 476 (1965).

    CAS  Google Scholar 

  10. Marks, P. A., Burka, E. R., and Schlessinger, D., Proc. U.S. Nat. Acad. Sci., 48, 2163 (1962).

    Article  ADS  CAS  Google Scholar 

  11. DeBellis, R. H., Gluck, N., and Marks, P. A., J. Clin. Invest., 43, 1329 (1964).

    Article  CAS  Google Scholar 

  12. Fanelli, A. R., Antonini, E., and Caputo, A., Biochim. Biophys. Acta, 30, 608 (1958).

    Article  CAS  Google Scholar 

  13. Clegg, J. B., Naughton, M. A., and Weatherall, D. J., Nature, 207, 945 (1965).

    Article  ADS  CAS  Google Scholar 

  14. Bray, G. A., Anal. Biochem., 1, 279 (1960).

    Article  CAS  Google Scholar 

  15. Huehns, E. R., Beaven, G. H., and Stevens, B. L., Biochem. J., 92, 440 (1964).

    CAS  PubMed  PubMed Central  Google Scholar 

  16. Colombo, B., and Baglioni, C., J. Mol. Biol., 16, 51 (1966).

    Article  CAS  Google Scholar 

  17. Fessas, P., and Loukopoules, D., Science, 143, 590 (1964).

    Article  ADS  CAS  Google Scholar 

  18. Fessas, P., Blood, 21, 21 (1963).

    Article  CAS  Google Scholar 

  19. Gabuzda, T. G., Nathan, D. G., and Gardner, F. H., J. Clin. Invest., 42, 1678 (1963).

    Article  CAS  Google Scholar 

  20. Marks, P. A., and Burka, E. R., Science, 144, 522 (1964).

    Article  ADS  Google Scholar 

  21. Ingram, V. M., Ann. N.Y. Acad. Sci., 119, 485 (1964).

    Article  ADS  CAS  Google Scholar 

  22. Itano, H. A., C.I.O.M.S. Symp. Abnormal Haemoglobins and Enzyme Deficiency (Blackwell Scientific Publications, Oxford, 1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BANK, A., MARKS, P. Excess α Chain Synthesis Relative to β Chain Synthesis in Thalassaemia Major and Minor. Nature 212, 1198–1200 (1966). https://doi.org/10.1038/2121198a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2121198a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing