Abstract
AN examination of several hundred white Wistar rats from the only source of laboratory animals available to this institution revealed a 100 per cent incidence of renal calcification in female animals and a complete absence of this condition in males of the species. This situation also applied to pure line white Wistar, black Wistar and black and white Wistar strains but was not observed in several species of mice from the same source and fed the identical diet.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Ludwig, T. G., Malthus, R. S., and Healy, W. B., Nature, 194, 456 (1962).
Steenbock, H., and Black, A., J. Biol. Chem., 64, 263 (1925).
Scarpelli, D. G., Lab. Invest., 14, 123 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
COUSINS, F., GEARY, C. A Sex-determined Renal Calcification in Rats. Nature 211, 980–981 (1966). https://doi.org/10.1038/211980b0
Issue Date:
DOI: https://doi.org/10.1038/211980b0
This article is cited by
-
Effect of age and dietary protein level on tissue mineral levels in female rats
Biological Trace Element Research (1996)
-
Nephrocalcinose und alkalische Nierenphosphatase
Klinische Wochenschrift (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
