Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Coagulant Activity of Tiger Snake (Notechis scutatus scutatus) Venom

Nature volume 211, pages 873–875 (1966)Cite this article

Abstract

TIGER snake venom has the ability to clot blood. Holden1 and Blömback2 have presented evidence that prothrombin, Factor V and calcium ions are required for the venom to convert fibrinogen to fibrin. We have studied the action of this venom on several purified clotting factors. As the crude venom was used in these experiments, the results obtained may arise from more than one active constituent present in the venom.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Holden, H. F., Austral. J. Exp. Biol. Med. Sci., 11, 1 (1933).

    Article  CAS  Google Scholar 

  2. Blömback, B., Thromb. Diath. Haem., Suppl., 17, 59 (1965).

    Google Scholar 

  3. Esnouf, M. P., and Williams, W. J., Biochem. J., 84, 62 (1962).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Jobin, F., thesis, Univ. Oxford (1965).

  5. Nahas, L., Denson, K. W. E., and Macfarlane, R. G., Thromb. Diath. Haem., 12, 355 (1964).

    Article  CAS  Google Scholar 

  6. Esnouf, M. P., and Jobin, F., Thromb. Diath. Haem., Suppl. 17, 103 (1965).

  7. Esnouf, M. P., and Jobin, F. (unpublished results).

  8. Quick, A. J., J. Biol. Chem., 109, lxxiii (1935).

  9. Spaet, T. H., and Cintron, J., Blood, 21, 745 (1963).

    CAS  PubMed  Google Scholar 

  10. Biggs, R., and Macfarlane, R. G., in Human Blood Coagulation and its Disorders, third ed., 389 and 397 (Blackwell Scientific Publications, Oxford, 1962).

    Google Scholar 

  11. Hensen, A., and Loeliger, E. A., Thromb. Diath. Haem., Suppl. 9 (1963).

Download references

Author information

Authors and Affiliations

  1. Nuffield Department of Clinical Biochemistry, University of Oxford, Radcliffe Infirmary, Oxford

    F. JOBIN & M. P. ESNOUF

Authors
  1. F. JOBIN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. P. ESNOUF
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

JOBIN, F., ESNOUF, M. Coagulant Activity of Tiger Snake (Notechis scutatus scutatus) Venom. Nature 211, 873–875 (1966). https://doi.org/10.1038/211873b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/211873b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing