Abstract
IN the rat, the fertilized egg normally loses its zona pellucida about 10 h after it reaches the uterus. Blastocysts flushed from the uterine cavity before 12 a.m. on the fifth day after the onset of a positive smearing reaction are still surrounded by their zonae, but those flushed in the early afternoon of the fifth day have lost their zonae1–3. Implantation begins some 6 h after the loss of the zona (110–114 h after ovulation)1.
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Psychoyos, A., C.R. Acad. Sci., Paris, 251, 3073 (1960).
Psychoyos, A., C.R. Acad. Sci., Paris, 252, 2306 (1961).
Dickmann, Z., and Noyes, R. W., Fert. and Ster., 12, 310 (1961).
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PSYCHOYOS, A. Influence of Oestrogen on the Loss of the Zona Pellucida in the Rat. Nature 211, 864 (1966). https://doi.org/10.1038/211864b0
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DOI: https://doi.org/10.1038/211864b0
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