Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Fine Structure of Experimentally Produced Subsynovial Carbon Granuloma

Nature volume 211, pages 771–772 (1966)Cite this article

Abstract

RECENT electron microscopic investigations of synovial joints have been concerned with the phagocytic nature of synovial membrane cells1,2. In order to investigate this phenomenon further, 1 c.c. of colloidal carbon in the form of Indian ink (particles 200–2000 Å in diameter) was injected into the knee joints of rabbits. 104 days later the animals were killed, and large granulomata were evident in the subsynovial tissues. This report is concerned with the structure of these carbon granulomata.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Barland, P., Novikoff, A. B., and Hamerman, D., J. Cell Biol., 14, 207 (1962).

    Article  CAS  Google Scholar 

  2. Ball, J., Chapman, J. A., and Muirden, K. D., J. Cell Biol., 22, 351 (1964).

    Article  CAS  Google Scholar 

  3. Sabatini, D. D., Bensch, K., and Barrnett, R. J., J. Cell Biol., 17, 19 (1963).

    Article  CAS  Google Scholar 

  4. Millonig, G., Fifth Intern. Congr. Electron Microscopy (Academic Press, New York, 1962).

    Google Scholar 

  5. Watson, M. L., J. Biophys. Biochem. Cytol., 1, 257 (1955).

    Article  CAS  Google Scholar 

  6. Reynolds, E. S., J. Biophys. Biochem. Cytol., 17, 208 (1963).

    Article  CAS  Google Scholar 

  7. Abercrombie, M., Heaysman, J. E. M., and Karthauser, H. M., Exp. Cell Res., 13, 276 (1957).

    Article  CAS  Google Scholar 

  8. Farquhar, M. G., and Palade, G. E., J. Cell Biol., 17, 375 (1963).

    Article  CAS  Google Scholar 

  9. Rosenbluth, J., and Palay, S. L., J. Biophys. Biochem. Cytol., 9, 853 (1961).

    Article  CAS  Google Scholar 

  10. Davis, J. M. G., Brit. J. Exp. Path., 44, 568 (1963).

    CAS  PubMed  Google Scholar 

  11. Haythorn, S. R., Archiv. Path., 7, 651 (1929).

    Google Scholar 

  12. Ham, A. W., and Lesson, T. S., Histology, fourth ed., 253 (J. B. Lippincott Co., Philadelphia, 1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anatomy, Michigan State University, East Lansing, Michigan

    WILLIAM S. ADAM

Authors
  1. WILLIAM S. ADAM
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

ADAM, W. Fine Structure of Experimentally Produced Subsynovial Carbon Granuloma. Nature 211, 771–772 (1966). https://doi.org/10.1038/211771a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/211771a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing