Abstract
ABORTIONS in cattle have been reported to occur as a result of nitrate poisoning1. Although the exact cause of death has not been elucidated, anoxia due to methaemoglobinaemia is believed to be responsible. Recently a transient deficiency of reduced diphosphopyridine nucleotide (DPNH)-dependent diaphorase in infants has been demonstrated, and it has been suggested that this may be a major cause of the increased susceptibility of newly born babies and animals to acquired methaemoglobinaemia2. It was also suggested that even lower enzyme activity would be encountered in foetal erythrocytes2. The present investigation was undertaken to determine whether the abortions occurring in nitrate poisoning of cattle could be related to foetal erythrocyte diaphorase levels.
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References
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SMITH, J., BEUTLER, E. Reduced Diphosphopyridine Nucleotide-dependent Diaphorase in Foetal, Newborn and Adult Cattle. Nature 211, 756–757 (1966). https://doi.org/10.1038/211756a0
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DOI: https://doi.org/10.1038/211756a0
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