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A Computer Programme for Automatic Scanning of Autoradiographs and Microradiographs of Bone Sections

Abstract

AUTORADIOGRAPHY of bone has played an important part in the investigation of the distribution of boneseeking isotopes. A measure of the non-uniformity of this distribution is of paramount importance in determining local radiation doses in bone and adjacent soft tissues. In addition, a comparison of autoradiographic and microradiographic pictures can provide information about bone resorption and bone turnover. Until recently these measurements have been severely limited in scope because of the tedious and time-consuming nature of such analyses. With advances in automatic densitometry and computers, these analyses have now become practicable on a much wider scale.

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References

  1. Hodges, D., Argonne Nat. Lab. Tech. Memo., No. 61 (1963).

  2. Butler, J. W., Butler, M. K., and Stroud, A., Proc. Conf. on Data Acquisition and Processing in Biology and Medicine (Pergamon Press, 1964).

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LLOYD, E., MARSHALL, J., BUTLER, J. et al. A Computer Programme for Automatic Scanning of Autoradiographs and Microradiographs of Bone Sections. Nature 211, 661–662 (1966). https://doi.org/10.1038/211661a0

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  • DOI: https://doi.org/10.1038/211661a0

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