Abstract
EVIDENCE has been presented, from investigations involving techniques of nuclear transfer and injections of cytoplasm, that certain cellular properties of Amoeba proteus and Amoeba discoides, such as nuclear diameter and sensitivity to streptomycin, are influenced by self-replicating cytoplasmic hereditary determinants1–6. The finding of DNA- and RNA-containing bodies in the cytoplasm of Amoeba proteus7–9, followed by the demonstration that these bodies are self-replicating within the cell8,9 and that they show a certain degree of interaction with the nucleus of amoeba8, has stimulated interest in the possibility that they contain the physical basis of this cytoplasmic inheritance6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lorch, I. J., and Danielli, J. F., Nature, 166, 329 (1950).
Lorch, I. J., and Danielli, J. F., Quart. J. Micros. Sci., 94, 461 (1953).
Danielli, J. F., Lorch, I. J., Ord, M. J., and Wilson, E. G., Nature, 176, 1114 (1955).
Hawkins, S. E., Cole, R. J., and Danielli, J. F., Nature, 196, 396 (1962).
Cole, R. J., and Danielli, J. F., Exp. Cell Res., 29, 199 (1963).
Hawkins, S. E., and Cole, R. J., Exp. Cell Res., 37, 26 (1965).
Rabinovitch, M., and Plaut, W., J. Cell Biol., 15, 525 (1962).
Rabinovitch, M., and Plaut, W., J. Cell Biol., 15, 535 (1962).
Wolstenholme, D. R., and Plaut, W., J. Cell Biol., 22, 505 (1964).
Prescott, D. M., and James, T., Exp. Cell Res., 8, 256 (1955).
Mandel, referred to as a personal communication in ref. 9.
Lederberg, J., Physiol. Revs., 32, 403 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WOLSTENHOLME, D. Cytoplasmic Deoxyribonucleic Acid-containing Bodies in Amoebae. Nature 211, 652–653 (1966). https://doi.org/10.1038/211652b0
Issue Date:
DOI: https://doi.org/10.1038/211652b0
This article is cited by
-
Nuclear Transplantation Studies of the Action of Dimidium Bromide on Amoebae
Nature (1969)
-
Transmission of Cytoplasmic Determinants in Amoebae by Micro-injection of RNA-containing Fractions
Nature (1969)
-
Cytoplasmic DNA-containing Bodies and the Inheritance of Certain Cytoplasmically Determined Characters in Amoeba
Nature (1967)
-
Electron microscopic identification of the interphase chromosomes of Amoeba proteus and Amoeba discoides using autoradiography; with some notes on helices and other nuclear components
Chromosoma (1966)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.