Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Chronic Fluorosis in the Guinea-pig

Abstract

DEATHS often reaching epidemic proportion occurred in at least eight major guinea-pig breeding units in Sydney and Canberra during 1964 and early 1965. Affected animals were characterized by loss of weight, depression, inappetence, a marked slobbering causing saturation and often excoriation of the chin, neck and venter, and ultimate death. All ages were affected, but newly-weaned animals and pregnant or post-parturient females appeared especially susceptible. Decrease in weight was evident for 1 to several weeks until increasing loss of fluid from the oral cavity presaged death within 5–20 days.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Pirtle, E. C., and McKee, A. P., Proc. Soc. Exp. Biol. and Med., 77, 425 (1951).

    Article  CAS  Google Scholar 

  2. Paterson, J. S., Proc. Nutrit. Soc., 16, 83 (1957).

    Article  CAS  Google Scholar 

  3. Galloway, J. D., Glover, D., and Fox, W. C., Lab. Animal Care, 14, 6 (1964).

    CAS  Google Scholar 

  4. Phillips, P. H., J. Biol. Chem., 100, 79 (1933).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ATKINSON, F., HARD, G. Chronic Fluorosis in the Guinea-pig. Nature 211, 429–430 (1966). https://doi.org/10.1038/211429a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/211429a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing