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Roles of Phosphate and Respiration in Nuclear Damage in Irradiated Rat Thymocytes

Abstract

THE highly radiosensitive thymic lymphocyte (or thymocyte) suffers true physiological death shortly after irradiation with relatively low doses of X-rays. The most striking symptom of radiation damage is the loss of nuclear structure (pycnosis); the prominent chromatin granules and threads of the interphase nucleus disperse and form a structurally homogeneous basophilic mass1.

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WHITFIELD, J., YOUDALE, T. Roles of Phosphate and Respiration in Nuclear Damage in Irradiated Rat Thymocytes. Nature 211, 212–213 (1966). https://doi.org/10.1038/211212b0

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