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Effect of Oestrogen on the Small Pigmented Spots in Hamsters

Abstract

IN Syrian golden hamsters pigmented melanocytes of the skin are mainly restricted to the hair bulbs and occasional networks surrounding pilosebaceous units1. These melanocytic networks are seen as small pigmented spots in whole mounts of hamster skin. Because these spots bear some resemblance to melanotic naevi in man2, and develop into melanomas when painted with chemical carcinogens1,3 they have been the subject of extensive investigations in recent years.

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References

  1. Ghadially, F. N., and Barker, J. F., J. Path. Bact., 79, 263 (1960).

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  2. Ghadially, F. N., Experientia, 16/7, 312 (1960).

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  3. Illman, O., and Ghadially, F. N., Brit. J. Cancer, 14, 483 (1960).

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ILLMAN, O., GHADIALLY, F. Effect of Oestrogen on the Small Pigmented Spots in Hamsters. Nature 211, 1303–1304 (1966). https://doi.org/10.1038/2111303a0

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