Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Examination of Isoenzymes of Several Dehydrogenases in Pure Cell Lines

Abstract

MANY workers have demonstrated that lactic acid dehydrogenase (LDH) and malic acid dehydrogenase (MDH) exist in several isoenzyme forms1–5. Bands of different electrophoretic mobility have also been reported for 6-phosphogluconate dehydrogenase (6-PGDH) (ref. 6), but the kinetic properties of these isoenzymes have not been as clearly defined.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Markert, C. L., and Moller, F., Proc. U.S. Nat. Acad. Sci., 45, 753 (1959).

    Article  ADS  CAS  Google Scholar 

  2. Kaplan, N. O., Bact. Rev., 27, 155 (1963).

    CAS  PubMed  Google Scholar 

  3. Vessell, E., and Bearn, A. G., Ann. N.Y. Acad. Sci., 75, 286 (1958).

    Article  ADS  Google Scholar 

  4. Thorne, C. J. R., Grossman, L. I., and Kaplan, N. O., Biochim. Biophys. Acta, 73, 193 (1963).

    Article  CAS  Google Scholar 

  5. Sawaki, S., Morikawa, N., and Yamada, K., Nature, 207, 523 (1965).

    Article  ADS  CAS  Google Scholar 

  6. Fildes, R. A., and Parr, C. W., Nature, 200, 890 (1963).

    Article  ADS  CAS  Google Scholar 

  7. Fischer, G. A., Ann. N.Y. Acad. Sci., 76, 673 (1958).

    Article  ADS  CAS  Google Scholar 

  8. Goldenberg, G. J., and Alexander, P., Cancer, Res., 25, 1401 (1965).

    CAS  Google Scholar 

  9. MacPherson, I. A., and Stoker, M. G. P., Virology, 16, 147 (1962).

    Article  CAS  Google Scholar 

  10. Barski, G., and Wolff, E., J. Nat. Cancer Inst., 34, 495 (1965).

    CAS  PubMed  Google Scholar 

  11. Fine, L. H., Kaplan, N. O., and Kuftinec, D., Biochemistry, 2, 116 (1963).

    Article  CAS  Google Scholar 

  12. Vessell, E., Phillips, J., and Bearn, A. G., J. Exp. Med., 116, 797 (1962).

    Article  Google Scholar 

  13. Cahn, R. D., Develop. Biol., 9, 327 (1964).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

YASIN, R., GOLDENBERG, G. Examination of Isoenzymes of Several Dehydrogenases in Pure Cell Lines. Nature 211, 1296–1297 (1966). https://doi.org/10.1038/2111296a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2111296a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing