Abstract
SINCE Leloir and Cardini1 showed that glycogen was synthesized from uridine diphosphate–glucose (UDPG) by liver extracts, it has become commonly accepted2,3 that the normal mechanism of glycogen synthesis in liver and muscle does not involve a reversal of the phosphorylase reaction but the following sequence of reactions:
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References
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THRELFALL, C. Role of Glucose 6-phosphate in the Synthesis of Glycogen by the Rat Liver in vivo. Nature 211, 1192 (1966). https://doi.org/10.1038/2111192a0
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DOI: https://doi.org/10.1038/2111192a0
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