Abstract
THE prototype strain (WBR 1) of bovine adenovirus type 3 (ref. 1) is pathogenic for colostrum-deprived calves2, and serological evidence indicates that, in addition to bovine adenovirus types 1 and 2, this serotype is involved in natural outbreaks of respiratory disease in cattle3. It has now been shown that the WBR 1 strain can induce the formation of tumours in hamsters, a capacity shared by certain other adenoviruses including human types 3, 7, 12, 18 and 31 (refs. 4–8), the chick embryo lethal orphan (CELO) virus9 and a number of simian adenoviruses10.
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DARBYSHIRE, J. Oncogenicity of Bovine Adenovirus Type 3 in Hamsters. Nature 211, 102 (1966). https://doi.org/10.1038/211102a0
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DOI: https://doi.org/10.1038/211102a0
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