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Effect of Ultra-violet Irradiation on Skin Collagen

Nature volume 211, pages 97–98 (1966)Cite this article

Abstract

Bottoms and Shuster1 have shown that when hairless mouse skin is exposed to ultra-violet irradiation in vitro there is a decrease in the saline and citrate soluble collagen fractions; however, the insoluble collagen remains unchanged. At the same time, there is an increase in the toughness of the pelts. It was suggested that these effects of ultra-violet irradiation were due to increased cross-linkage between the collagen fibrils. In the experiments described here, we attempted to measure the degree of cross-linkage of mouse skin and kangaroo tail tendon collagen before and after ultra-violet irradiation.

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References

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Author information

Authors and Affiliations

  1. Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne

    EVA BOTTOMS

  2. British Leather Manufacturers Research Association, Milton Park, Egham, Surrey

    C. W. CATER

  3. Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne

    SAM SHUSTER

Authors
  1. EVA BOTTOMS
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  2. C. W. CATER
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  3. SAM SHUSTER
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BOTTOMS, E., CATER, C. & SHUSTER, S. Effect of Ultra-violet Irradiation on Skin Collagen. Nature 211, 97–98 (1966). https://doi.org/10.1038/211097a0

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  • DOI: https://doi.org/10.1038/211097a0

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