Abstract
SOME years ago Brecher and Waxier1 described for the first time obesity in mice resulting from aurothioglucose (ATG) injection. Since then it has been found that ATG can cause lesions in different areas of the brain2–4. Among these, the lesions in the ventromedian hypothalamic nuclei are held responsible for the observed obesity. However, it was also found that the most effective ATG doses caused a high mortality5.
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WIEPKEMA, P. Aurothioglucose Sensitivity of CBA Mice injected at Two Different Times of Day. Nature 209, 937 (1966). https://doi.org/10.1038/209937a0
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DOI: https://doi.org/10.1038/209937a0
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