Abstract
FLUOROACETATE or fluoroacetamide, after conversion to fluorocitrate, inhibit aconitase1 and therefore block the tricarboxylic acid cycle; consequently these chemicals are toxic to animals and are used as pesticides. There have been at least two occasions when accidental contamination of soil and water by fluoracetamide has occurred2. This communication reports the isolation of bacteria able to use these compounds for growth.
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References
Peters, R. A., Adv. Enzymol., 17, 113 (1957).
Hansard, 688–9 (612), 333 (1964).
Kelly, M., and Clarke, P. H., J. Gen. Microbiol., 27, 315 (1962).
Snell, F. D., and Snell, C. T., Colorimetric Methods of Analysis, 2, 750 (D. Van Nostrand Company Inc., New York, 1949).
Snell, F. D., and Snell, C. T., Colorimetric Methods of Analysis, 4, 33 (D. Van Nostrand Company Inc., New York, 1949).
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KELLY, M. Isolation of Bacteria able to metabolize Fluoroacetate or Fluoroacetamide. Nature 208, 809–810 (1965). https://doi.org/10.1038/208809a0
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DOI: https://doi.org/10.1038/208809a0
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