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Decay of Immunological Responsiveness after Thymectomy in Adult Life

Abstract

THE remarkable effects of neonatal thymectomy are by now well documented1. Primary among these is a failure of the lymphoid tissues to develop properly, which is marked particularly by a deficiency of small lymphocytes. Other features, probably resulting from this, include a defective capacity to perform all kinds of immune responses, and a progressive wasting disease ending in early death.

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TAYLOR, R. Decay of Immunological Responsiveness after Thymectomy in Adult Life. Nature 208, 1334–1335 (1965). https://doi.org/10.1038/2081334a0

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