Abstract
CITRUS fruits contain several nitrogenous bases which are important compounds in human metabolism and have interesting pharmacological properties. Two such compounds recently identified in citrus, not reported previously in other plants, are octopamine and synephrine1,2. A continuation of the investigation of basic nitrogen compounds in citrus has resulted in the isolation and identification of feruloylputrescine (N-(4-aminobutyl)-4-hydroxy-3-methoxycinnamamide), originally called subaphylline : 
This compound, found in leaves and juice of grapefruit, Citrus paradisi Macf., also has interesting pharmacological properties and has been reported previously only in the unrelated plant, Salsola subaphylla3.
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WHEATON, T., STEWART, I. Feruloylputrescine : Isolation and Identification from Citrus Leaves and Fruit. Nature 206, 620–621 (1965). https://doi.org/10.1038/206620a0
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DOI: https://doi.org/10.1038/206620a0
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