Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Reduction of Radiosensitivity of Antibody Response by Prior Administration of Non-cross-reacting Antigen

Nature volume 206, pages 416–418 (1965)Cite this article

Abstract

THE susceptibility of the antibody-forming mechanism to ionizing radiations has been known to tend to decrease with the lapse of time after antigenic stimulation1–3. This implies that some early events in immune response, such as the engulfment of antigen by phagocytic cells4 or the proliferation of immunologically competent cells resulting in the multiplication of antibody-forming cells5, is injured by exposing the immunized animal to the radiation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Taliaferro, W. H., and Taliaferro, L. G., J. Infect. Dis., 95, 134 (1954).

    Article  CAS  PubMed  Google Scholar 

  2. Gengozian, N., and Makinodan, T., J. Immunol., 80, 189 (1958).

    CAS  PubMed  Google Scholar 

  3. Makinodan, T., Friedberg, B. H., Tolboert, M. G., and Gengozian, N., J. Immunol., 83, 184 (1959).

    CAS  PubMed  Google Scholar 

  4. Muramatsu, S., Morita, T., and Sohmura, Y., Fourth Intern. Symp. on RES. (in the press).

  5. Makinondan, T., and Albright, J. F., J. Cell. Comp. Physiol., 60 (Supp. 1), 129 (1960).

    Article  Google Scholar 

  6. Muramatsu, S., Nature, 201, 1141 (1964).

    Article  CAS  ADS  PubMed  Google Scholar 

  7. Stavitsky, A. B., J. Immunol., 72, 360 (1954).

    CAS  PubMed  Google Scholar 

  8. Strauch, D., and Winter, H., Effects of Ionizing Radiation on Immune Processes, 315 (Gordon and Beach Sci. Pub., N.Y., 1962).

    Google Scholar 

  9. Burnet, M., The Clonal Selection Theory of Acquired Immunity (Camb. Univ. Press, 1959).

    Book  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Radiation Biology, Faculty of Science, Kyoto University, Japan

    S. MURAMATSU & Y. SOHMURA

Authors
  1. S. MURAMATSU
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Y. SOHMURA
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

MURAMATSU, S., SOHMURA, Y. Reduction of Radiosensitivity of Antibody Response by Prior Administration of Non-cross-reacting Antigen. Nature 206, 416–418 (1965). https://doi.org/10.1038/206416a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/206416a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing