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Dissociation of Facilitatory Mechanisms in the Midpontile Decerebrate Cat

Abstract

VAGOTOMIZED, midpontile decerebrate animals have been reported to exhibit decerebrate rigidity, apneustic breathing, tachycardia and arterial hypertension1,2. These manifestations of hyperactivity in the somatic postural, respiratory, and cardiovascular systems are abolished by transections of the central neuraxis at or caudal to the level of the pontomedullary junction1. These parallelisms suggest the hypothesis that interdependent if not identical facilitatory mechanisms in the lower pons are responsible for these hyperactive states. This hypothesis has been experimentally tested here.

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GLASSER, R., TIPPETT, J. Dissociation of Facilitatory Mechanisms in the Midpontile Decerebrate Cat. Nature 205, 810–811 (1965). https://doi.org/10.1038/205810a0

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