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Breakdown of Caffeine in the Leaves of Coffea arabica L.

Abstract

THE caffeine content of older Coffea leaves decreases after an initial increase in young leaves1. There are two possible explanations of this fact; first, a chemical transformation of caffeine; secondly, a translocation from the leaf to other organs. The object of these investigations was to find out if there is a breakdown of caffeine in the Coffea leaves and what compounds are formed. Four differently labelled caffeine molecules were synthesized, two with 14C in the purine ring (pos. 2 and 8) and two with 14C in the methyl groups (N1-methyl 14C and N7-methyl 14C).

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References

  1. Wanner, H., Alkaloid-Symposium, Halle (Saale), 1960.

  2. Kalberer, P., Ber. Schweiz. Bot. Ges. (in the press).

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KALBERER, P. Breakdown of Caffeine in the Leaves of Coffea arabica L.. Nature 205, 597–598 (1965). https://doi.org/10.1038/205597a0

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