Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Colicin 15: Possibly a Defective Bacteriophage

Abstract

COLICINS, bactericidal agents elaborated by many strains of the Enterobacteriaceae, have been classified as antibiotics1. Purified preparations of four colicins have been identified as lipocarbohydrate proteins2–5; a fifth apparently lacks the lipid component6. This communication presents evidence that an inducible colicin from Escherichia coli, WT15 (ref. 7), may be a defective bacteriophage.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Fredericq, P., The Biological Replication of Macromolecules, 104 (Academic Press, Inc., New York, 1958).

    Google Scholar 

  2. Barry, G. T., Everhart, D. L., and Graham, M., Nature, 198, 211 (1963).

    Article  ADS  CAS  Google Scholar 

  3. Goebel, W. F., and Barry, G. T., J. Exp. Med., 107, 185 (1958).

    Article  CAS  Google Scholar 

  4. Hutton, J. J., Goebel, W. F., Proc. U.S. Nat. Acad. Sci., 47, 1498 (1961).

    Article  ADS  CAS  Google Scholar 

  5. Nüske, R., Hösel, G., Venner, H., and Zinner, H., Biochem. Z., 329, 346 (1957).

    PubMed  Google Scholar 

  6. Reeves, P. R., Austral. J. Exp. Biol., 41, 163 (1963).

    Article  CAS  Google Scholar 

  7. Mukai, F. H., J. Gen. Microbiol., 23, 539 (1960).

    Article  CAS  Google Scholar 

  8. Ryan, F. J., and Schneider, L. K., Genetics, 34, 72 (1949).

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Goebel, W. F., Proc. U.S. Nat. Acad. Sci., 48, 214 (1962).

    Article  ADS  CAS  Google Scholar 

  10. Fredericq, P., J. Theoret. Biol., 4, 159 (1963).

    Article  CAS  Google Scholar 

  11. Kellenberger, G., and Kellenberger, E., Schweiz. Z. Path. Bakt., 19, 582 (1956).

    CAS  Google Scholar 

  12. Ivanovics, G., Bact. Rev., 26, 108 (1962).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

SANDOVAL, H., REILLY, H. & TANDLER, B. Colicin 15: Possibly a Defective Bacteriophage. Nature 205, 522–523 (1965). https://doi.org/10.1038/205522a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/205522a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing