Abstract
IT is generally admitted that mice undergoing graft-versus-host reaction reveal diminished immunological competence. In particular, the antibody production following antigenic challenge is known to be depressed1–3, although there is little conclusive evidence concerning the behaviour of immunoglobulins4,5. This particular aspect of the graft-versus-host reaction has been examined by us.
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References
Howard, J. G., and Woodruff, M. F. A., Proc. Roy. Soc., B, 154, 532 (1962).
Oliner, H., Schwartz, R., and Dameshek, W., Blood, 17, 20 (1961).
Good, R. A., Kelly, W. D., and Gabrielsen, A. F., in Mechanism of Cellular and Tissue Damage Produced in Immune Reactions. II, Intern. Symp. Immunopathology, edit. by Grabar, P., and Miescher, P., 352 (Schwave Co., Basel-Stuttgart, 1962).
Blaese, M., Martinez, C., and Good, R. A., J. Exp. Med., 119, 211 (1964).
Simonsen, M., Progr. Allergy, 6, 349 (1958).
Mansi, W., Nature, 181, 1289 (1958).
Arnason, B. G., Vaux St. Cyr, C., and Shaffner, J. B. (to be published).
Lowry, O. H., Rosenbrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Itoh, T., and Southam, C., J. Immunol., 91, 469 (1963).
Fahey, J. L., Wunderlich, J., and Mishell, R., J. Exp. Med., 120, 2, 223 (1964).
Fahey, J. L., Wunderlich, J., and Mishell, R., J. Exp. Med., 120, 2, 243 (1964).
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KOLTAY, M., KINSKY, R. & ARNASON, B. Immunoglobulin-levels in Mice undergoing Graft-versus-host Reaction. Nature 205, 509–510 (1965). https://doi.org/10.1038/205509a0
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DOI: https://doi.org/10.1038/205509a0
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