Abstract
AS autoradiographic examination of human and other mammalian chromosomes after incorporation of tritiated thymidine has revealed a characteristic pattern of replication during the late S phase for the heteropycnotic X chromosome and some autosomes, the lymphocyte culture technique associated with a simplified autoradiographic method may be used for diagnosis and investigations of the sex chromosomes even in smaller laboratories.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lucas, M., Kemp, N. H., Ellis, J. R., and Marshall, R., Ann. Hum. Genet., 27, 189 (1963).
Gropp, A., Jussen, A., and Ofteringer, K., Nature, 202, 829 (1964).
Muldal, S., Gilbert, C. W., Lajtha, L. G., Lindsten, J., Rowley, J., and Fraccaro, M., Lancet, i, 861 (1963).
Rowley, J., Muldal, S., Lindsten, J., and Gilbert, C. W., Proc. U.S. Nat. Acad. Sci., 51, 779 (1964).
Giannelli, F., Lancet, i, 853 (1963).
Atkins, L., and Gustavson, K. H., Hereditas, 51, 135 (1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PFEIFFER, R., BÜCHNER, T. Absence of Late Replication of a Human X-Ring Chromosome. Nature 204, 804–805 (1964). https://doi.org/10.1038/204804b0
Issue Date:
DOI: https://doi.org/10.1038/204804b0
This article is cited by
-
Translocation X sur autosome et replication tardive
Human Genetics (1975)
-
Directed Genetic Change Model for X Chromosome Inactivation in Eutherian Mammals
Nature (1971)
-
Osteodystrophia hereditaria Albright und Ullrich-Turner-Syndrom
Archiv f�r Gyn�kologie (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
