Abstract
MUSCLE owes its morphological and biochemical identity to proteins such as actin, myosin, tropomyosin, etc.,1 and it is reasonable to suspect that these molecules are somehow represented in the genome. Until rather recently, it was generally believed that all new proteins are manufactured by freshly made messenger RNA's of exceedingly short half-lives. However, recently it has become rather evident that there are at least a few systems in which genetic messages are sent many generations before they are used2. Is this the case with myogenesis, or is the necessary information for muscle differentiation sent shortly before it is called into play ?
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PIETSCH, P. Time-dependent Inhibition of Myogenesis by Actinomycin D. Nature 203, 1177 (1964). https://doi.org/10.1038/2031177a0
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DOI: https://doi.org/10.1038/2031177a0
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