Abstract
MODIFICATION of erythrocytes in vitro by various enzymatic or chemical treatments renders them agglutinable by normal sera from mature donors. This agglutination reaction is called ‘panagglutination’1,2. In the course of our investigation on the specific reaction of azohaptenerythrocytes with antisera against azohaptens3, we observed that after coupling erythrocytes with diazotized p-nitroaniline (PNA), they were agglutinated by normal rabbit serum absorbed with untreated erythrocytes3. This communication deals with the finding of a similar phenomenon with human serum.
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References
Springer, G. F., Bact. Rev., 27, 191 (1963).
Uhlenbruck, G., Zbl. Bakter, 179, 229 (1961).
Timpl, R., Wolff, I., and Steffen, C., Z. Immunitaetsforsch., 125, 152 (1963).
Pennell, R. B., in The Plasma Proteins, edit. by Putnam, F. W., 1, 18 (Academic Press, New York and London, 1960).
Burnet, F. M., and Anderson, S. G., Austral. J. Exp. Biol. Sci. 25, 213 (1947).
Rosenthal, M. C., and Schwartz, L. J., Proc. Soc. Exp. Biol. Med., 76, 635 (1951).
Moskowitz, M., and Treffers, H. P., Science, 111, 717 (1950).
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WOLFF, I., TIMPL, R. & STEFFEN, C. Panagglutination of Erythrocytes coupled with Diazotized p-Nitroaniline. Nature 203, 1076–1077 (1964). https://doi.org/10.1038/2031076a0
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DOI: https://doi.org/10.1038/2031076a0
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