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Iontophoretic Application of Gamma-Aminobutyric Acid on Crayfish Muscle

Abstract

IT has been observed that γ-aminobutyric acid (GABA) mimics the action of inhibitory transmitter in several crustacean muscles1–5. In these investigations the action of GABA was investigated by perfusing the preparation with solutions containing the drug, and iontophoretic micro-application of GABA to these preparations was not performed. The latter has advantages over the perfusion experiment in providing localized application of the drug and more precise control of its duration.

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References

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TAKEUCHI, A., TAKEUCHI, N. Iontophoretic Application of Gamma-Aminobutyric Acid on Crayfish Muscle. Nature 203, 1074–1075 (1964). https://doi.org/10.1038/2031074a0

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