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Stability of a Synthetic Polyribosome Complex in the Cell-free System

Abstract

DURING polyuridylic acid-stimulated phenylalanine incorporation by E. coli cell-free systems, complexes are formed between polyuridylic acid (poly-U) and ribosomal monomers1–3. Evidence has been reported of similar complex formation in the rabbit reticulocyte cell-free system4. Such complexes, which result from the attachment of two or more ribosomes to the same poly-U molecule5, are thought to be analogous to the naturally occurring polysome complexes which can be isolated from mammalian6–9 and other10–12 cells.

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BISHOP, J. Stability of a Synthetic Polyribosome Complex in the Cell-free System. Nature 202, 86–88 (1964). https://doi.org/10.1038/202086a0

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