Abstract
DURING polyuridylic acid-stimulated phenylalanine incorporation by E. coli cell-free systems, complexes are formed between polyuridylic acid (poly-U) and ribosomal monomers1–3. Evidence has been reported of similar complex formation in the rabbit reticulocyte cell-free system4. Such complexes, which result from the attachment of two or more ribosomes to the same poly-U molecule5, are thought to be analogous to the naturally occurring polysome complexes which can be isolated from mammalian6–9 and other10–12 cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Barondes, S. H., and Nirenberg, M. W., Science, 138, 813 (1962).
Hasehemeyer, A. E. V., and Rich, A., Biochim. Biophys. Acta, 55, 994 (1962).
Spyrides, G. J., and Lipmann, F., Proc. U.S. Nat. Acad. Sci., 48, 1977 (1962).
Weinstein, I. B., Schechter, A. N., Burka, E. R., and Marks, P. A., Science, 340, 314 (1963).
Gilbert, W., J. Mol. Biol., 6, 389 (1963).
Gierer, A., J. Mol. Biol., 6, 148 (1963).
Marks, P. A., Burka, E. R., and Schlessinger, D., Proc. U.S. Nat. Acad. Sci., 48, 2163 (1962).
Warner, J. R., Knopf, P. M., and Rich, A., Proc. U.S. Nat. Acad. Sci., 49, 122 (1963).
Wettstein, F. O., Staehelin, T., and Noll, H., Nature, 197, 430 (1963).
Gilbert, W., J. Mol. Biol., 6, 374 (1963).
Schaechter, M., J. Mol. Biol., 7, 561 (1963).
Schlessinger, D., J. Mol. Biol., 7, 569 (1963).
Noll, H., Staehelin, T., and Wettstein, F., Nature, 198, 632 (1963).
Goodman, H. M., and Rich, A., Nature, 199, 318 (1963).
Bishop, J. O. (submitted for publication).
Martin, R. G., and Ames, B. N., J. Biol. Chem., 236, 1372 (1961).
Hardesty, B., Miller, R., and Schweet, R., Proc. U.S. Nat. Acad. Sci., 50, 924 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BISHOP, J. Stability of a Synthetic Polyribosome Complex in the Cell-free System. Nature 202, 86–88 (1964). https://doi.org/10.1038/202086a0
Issue Date:
DOI: https://doi.org/10.1038/202086a0
This article is cited by
-
Reticulocyte Ribosome Fraction with an Exceptional Capacity for Polyphenylalanine Synthesis
Nature (1965)
-
Über Struktur und Funktion des genetischen Materials
Die Kulturpflanze (1965)
-
Initiation of Polypeptide Chains in the Reticulocyte Cell-Free System
Nature (1964)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.