Abstract
EVIDENCE has been obtained that the addition of sodium to the diet of animals in which hypertension has been induced aggravates the hypertension and the renal lesions. Similar observations were made in man. Moreover, a salt-poor diet or the administration of natridiuretics lower experimental and clinical hypertension. It has already been reported1,2 that, in rats rendered hypertensive, an accumulation of sodium in the arterial walls is frequently observed.
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HALPERN, B., MILLIEZ, P., MEYER, P. et al. Increase in Sodium Content in the Arterial Walls during Experimental Hypertension. Nature 201, 505 (1964). https://doi.org/10.1038/201505a0
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DOI: https://doi.org/10.1038/201505a0
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