Abstract
THE problem of the excitation-contraction link in muscle cells has long been one of the chief fields of modern muscle physiology1–4. Of many reports in this field, one of the most interesting was the demonstration of the inhibition of the linking function due to the osmotically hypertonic condition, as demonstrated by Hodgkin and Horowicz3. Though this demonstration is striking, it does not help to analyse the linking system, since the condition used is rather unspecific. It seems to be of importance to search for substances which may remove the inhibitory effect of the hypertonic condition. This communication deals with the problem and demonstrates that the potassium ion has the aforementioned removing effect.
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References
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FUJINO, S., FUJINO, M. Removal of the Inhibitory Effect of Hypertonic Solutions on the Contractibility in Muscle Cells and the Excitation-contraction Link. Nature 201, 1331–1333 (1964). https://doi.org/10.1038/2011331a0
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DOI: https://doi.org/10.1038/2011331a0
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