Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Independence of the Formation of Extracellular Protease on the Amino-acid Level in the Cells of Bacillus megatherium

Abstract

SYNTHESIS of extracellular protease in micro-organisms is repressed in the presence of free amino-acids in the medium1–3. However, the formation of intracellular enzyme is not influenced by amino-acids. The quantitative relationship between the amount of amino-acids present in the medium, their level in the cells and inhibition of enzyme formation was investigated during short-time incubation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Chaloupka, J., Folia Biologica, 2, 72 (1956).

    CAS  Google Scholar 

  2. Chaloupka, J., and Křečková, P., Biochim. Biophys. Res. Com., 8, 120 (1962).

    Article  CAS  Google Scholar 

  3. Neumark, R., and Citri, N., Biochim. Biophys. Acta, 59, 749 (1962).

    Article  CAS  Google Scholar 

  4. McQuillen, K., Biochim. Biophys. Acta, 18, 458 (1955).

    Article  CAS  Google Scholar 

  5. Chaloupka, J., Liebster, J., and Janeček, J., Proc. Second Intern. Conf. Peaceful Uses of Atomic Energy, Geneva, 25, 140 (1958).

    Google Scholar 

  6. Gale, E. F., J. Gen. Microbiol., 1, 53 (1947).

    Article  CAS  Google Scholar 

  7. Moore, S., and Stein, W. H., J. Biol. Chem., 211, 893 (1954).

    CAS  PubMed  Google Scholar 

  8. Gorini, L. (personal communication).

  9. Burger, M., and Pavlasová, E. (in the press).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CHALOUPKA, J., KŘEČKOVÁ, P. & ŘÍHOVÁ, L. Independence of the Formation of Extracellular Protease on the Amino-acid Level in the Cells of Bacillus megatherium. Nature 200, 885–886 (1963). https://doi.org/10.1038/200885b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/200885b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing